Evolution of Nematode Vulval Fate Patterning
نویسندگان
چکیده
منابع مشابه
Cell fate patterning during C. elegans vulval development.
Precursor cells of the vulva of the C. elegans hermaphrodite choose between two vulval cell fates (1 degree and 2 degrees) and a non-vulval epidermal fate (3 degrees) in response to three intercellular signals. An inductive signal produced by the anchor cell induces the vulval precursors to assume the 1 degree and 2 degree vulval fates. This inductive signal is an EGF-like growth factor encoded...
متن کاملSpatial regulation of lag-2 transcription during vulval precursor cell fate patterning in Caenorhabditis elegans.
lag-2 encodes a ligand for LIN-12/Notch and is a component of the lateral signal that activates LIN-12/Notch during Caenorhabditis elegans vulval precursor cell (VPC) fate patterning. lag-2 is specifically transcribed in one VPC, named P6.p, in response to activation of EGFR/Ras/MAPK by the inductive signal that initiates vulval development. Here, we show that a critical molecular event linking...
متن کاملAn Atlas of Network Topologies Reveals Design Principles for Caenorhabditis elegans Vulval Precursor Cell Fate Patterning
The vulval precursor cell (VPC) fate patterning in Caenorhabditis elegans is a classic model experimental system for cell fate determination and patterning in development. Despite its apparent simplicity (six neighboring cells arranged in one dimension) and many experimental and computational efforts, the patterning strategy and mechanism remain controversial due to incomplete knowledge of the ...
متن کاملPolymorphism and evolution of vulval precursor cell lineages within two nematode genera, Caenorhabditis and Oscheius
BACKGROUND The cell lineage of nematodes is mostly invariant for a given species, but varies between species. One can thus wonder how a cell lineage varies during evolution. We have started a microevolutionary approach within two genera by observing lineage variations of vulval precursor cells in different natural nematode populations of the same and closely related species. RESULTS In Caenor...
متن کاملEvaluation of Some Vulval Appendages in Nematode Taxonomy
A survey of the nature and phylogenetic distribution of nematode vulval appendages revealed 3 major classes based on composition, position, and orientation that included membranes, flaps, and epiptygmata. Minor classes included cuticular inflations, protruding vulvar appendages of extruded gonadal tissues, vulval ridges, and peri-vulval pits. Vulval membranes were found in Mermithida, Triplonch...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 1996
ISSN: 0012-1606
DOI: 10.1006/dbio.1996.0035